MECHANISM OF ACTION (Click To Open)

Physical adsorption of Enterosgel, like most other enterosorbents such as activated charcoal, silica and polymers.

The core structure of main active component of Enterosgel polymethylsiloxane polyhydrate (PMSPH) comprises crumpled 2-dimensional sheets of tetrahedral -Si-O-Si-O-

The surface of nanoglobules has methyl (-CH3) and hydroxyl (-OH) groups bound to the atoms of silicon, Si.

The presence of hydrophilic groups (-OH) and hydrophobic groups (-CH3) makes this sorbent both hydrophilic and hydrophobic, which is rather unique compared with activated charcoal (mostly hydrophobic) and mineral sorbents such as silica (mostly hydrophilic). It allows PMSPH adsorb both hydrophilic and hydrophobic substances from aqueous solution.

The porous structure of polymer hydrogels such as PMSPH has been assessed by Gun’ko et al. (2007). The specific surface area of PMSPH is around 200 m2/g (dry weight). It has both micropores (below 2 nm in diameter) and mesopores (between 2 and 50 nm in diameter), with the mean mesopore diameter of 20 nm, which allows retention of small molecules in micropores and large biomolecules in mesopores. The surface area comprises almost equal contribution of both micro- and mesopores.

The Enterosgel® suspension of 10 g has therefore a surface area of approximately 2000 m2, which is sufficiently large to adsorb significant amount of substances of different molecular weight.

In vitro experiments described in Nikolaev, 2010 and Gun’ko et al., 2007, evaluated the adsorption capacity of PMSPH towards substances of different molecular weight in comparison with other materials used as enterosorbents such as activated charcoal and silica. It has been found that although the adsorption capacity of activated charcoal enterosorbents for small molecular weight substances tested (in the range from 60 Da (urea) to 1355 Da (vitamin B12) is significantly higher than that of PMSPH, the results were reverse for adsorption of large molecules of proteinaceous origin tested, from 23.3 kDa (trypsin) to 150 kDa (immunoglobulin G), with Enterosgel® paste showing 4-14 times higher adsorption capacity than the best activated charcoal and comparable values for adsorption of lipopolysaccharide, LPS calculated per daily dose.

Since the dose recommended for oral administration of PMSPH is substantially larger than that for activated charcoal by weight (approximately 3 times), the adsorption capacity of a daily dose of PMSPH towards small molecular weight substances becomes comparable to that of the daily dose of the latter.

The reason for the difference in the dosage between the two sorbents is the difference in their apparent density (activated charcoal has much lower apparent density hence the volume of the same weight of activated charcoal is about 3 times larger than the volume of PMSPH of the same weight).

The mechanism of this phenomenon has been discussed but there are no conclusive data to support it.

Enterosgel® does not incorporate any medicinal substance, or animal tissues, or blood components.

Millions of people use Enterosgel as a “pocket ambulance” that helps treat intoxication, allergy, IBS-D

DIARRHEA

Most interventions are ineffective as medication travels through the digestive system to be absorbed properly. Enterosgel is different. It doesn’t get absorbed by the body, but rather passes through and uses its porous structure to absorb and remove harmful pathogens from the body, therefore stopping fast diarrhea at its cause. It is effective against acute diarrhoea caused by bacterial infection, viral infection (including rotaviral), food poisoning, antibiotic-associated, irritable bowel syndrome (IBS) and more.

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ALLERGIES

Medical trials show, there was shortening of exacerbation period and complete relief of morphological elements on the skin and the achievement of clinical remission was observed in average on the 8th day from the start of therapy to receive Enterosgel combined with the standard conventional treatment.

ENTEROSGEL® is effective an adjuvant (ancillary) treatment for allergies with gastrointestinal symptoms to other standard conventional treatment for acute enteric intestinal complaints in children and adult.

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INDIGESTION

А. B. Petukhov et al. investigated the effectiveness of Enterosgel in the treatment of gastrointestinal diseases associated with indigestion and impaired absorption [1]. This trial enrolled adult patients with malabsorption syndrome, post-gastric resection syndrome, disorders following small intestinal resection and right-sided hemicolectomy, as well as patients with irritable bowel syndrome.

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INTOXICATION

The data obtained thus prove the effectiveness of enteral sorption with Enterosgel in the treatment of alcohol intoxication and withdrawal syndrome. Improvement in basic biological indicators was also observed.

Alcohol intoxication refers to the consequences of drinking characterized by appearance of reversible pathological mental, neurological and somatovegetative reactions associated with general toxic effects on the body, which is typically expressed by euphoria, sociability, relaxation and sedation. Effect of Enterosgel® depends on the time of its administration, the earlier Enterosgel is accepted, the more is the pronounced effect of its intake. Enterosgel is able to bind and excrete toxic products and endotoxins from the intestinal contents and blood (through the intestinal wall). Therefore, it is promising to study its efficiency in the treatment of patients with alcoholic liver disease (ALD).

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RADIONUCLIDES

Enterosgel promoted intensive release of radionuclides from the body tissues and their excretion in the adsorbed form with feces, which justifies the use of sorbent in contamination. Accelerated release of radionuclides was the result of a general detoxifying action of Enterosgel and process of their direct binding in the GIT lumen. Enterosgel provides effective detoxification, direct and indirect decorporation of radionuclides and improves the functional state of the liver. We have also proved that administration of Enterosgel at work in the radioactive contamination area can be seen as immunoprotective method with indirect mechanism of action. Enterosgel shows hepatoprotective effect in healthy people and to a lesser extent – in patients with chronic liver disease.

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TOXICOSIS

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BODY DETOX

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FACE CARE

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HEAVY METALS

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BY-PRODUCTS

The medications that can cause severe liver damage include even such widespread pharmaceuticals as paracetamol. Simultaneously, the advertisement and unrestricted sale of medication works towards its very wide application. Uncontrolled use of paracetamol is associated with a high risk of complications. According to data from medical centers in the USA and the UK, overdoses of paracetamol is one of the main causes of acute hepatic failure, which results in the death of patients in many cases.

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CANCER

Radiation therapy holds one of the main positions in the treatment of cancer patients. It is used in more than 80% of patients. In oncology, radiotherapy can be used alone or as part of combination therapy in the surgical / medical treatment. Because of the combined treatment, toxicity from chemotherapy joins body endogenous intoxication caused by radiotherapy. The use of endoscopy recanalization of intestinal lumen upon acute or partial colon obstruction in rectal cancer patients in combination with Enterosgel allows: quickly eliminate the symptoms of intestinal insufficiency syndrome; perform adequate chemoradiotherapy in preoperative period; facilitate the performance of primary reparative operation and the course of post-operative period; achieve significant decrease in the number of obstructive resections without worsening the prognosis of the main disease.

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FOR ATHLETES

Enterosgel has been tested by the Laboratory of the Government Chemist (LGC) for a wide range of substances banned by the World Anti Doping Agency (WADA) to provide the highest level of assurance that they are safer for athletes to use.

The Government Chemist (LGC) is a World Class sports doping control and research laboratory, with more than 50 years of leadership in drug surveillance in sport.

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DOG/CAT DIARRHEA

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E. COLI / H. PYLORI

V. N. Chernobrovyy and I. G. Paliy evaluated the potential of Enterosgel therapy in the treatment of large intestinal dysbiosis in the adult patients [1]. Fecal microbiology revealed intestinal dysbiosis in all study subjects: increased counts of E. coli haemolyticus and cocci, as well as positive tests for Klebsiella pneumoniae, S. аureus, and P. vulgaris.

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HOMEOPATHY

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NATUROPATIA

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Cleans toxics out of system

Very good for cleansing gut. Calmed my stomach down immediately.

Staci Miller
January 14, 2018

Works perfect

Enterosgel works perfect with any food poison.

Tati (CA, USA)
June 21, 2015

From tube is comfortable to use

the consistence is too rare.

there are another manufacture exist, which make one more solid.

Lyudmyla Hargrove
April 17, 2015

This product works for me

When I use the Enterosgel product consistently, it seems that it successfuly cuts down on allergies (skin rash) and infections.

Mrs. May I (Texas)
May 10, 2016

#1

This is the #1 most important supplement every human being should be taking.

Brooke
July 18, 2017

Recommend!

I would recommend this product to anyone with digestive or intestinal problems. We have also reduced our allergic complaints.

Adam
November 15, 2017

It does help!

It helped to combat an upset stomach. I believe it made quite a difference in how fast I recovered!
It is difficult to provide a measured comparison or evaluation. But at certain age you begin to know your body and its reactions. This gel did bring the real relief, way more powerful than for example an activated charcoal.

Serge (Bethany, OR)
March 3, 2017

It really does the job gently

Have been using for years.

Swimmer
February 12, 2014

It works

My friend told me to use this as a hangover treatment several years ago… well, too bad i did not listen then, because it works. This thing is a gel, so i take 2 table spoons and dissolve them in half a glass of water and drink it the night of… and then in the morning.. helps huge. I mean it’s not like i can drink the night away and wake up like i’ve been drinking carrot juice, no! But no throwing up, no terrible headache, no wanting to rather die… Yes, i still feel tiered, and still need to eat proper foods in the morning. But it helps and saves hangover time! I also used it during the party and it helped me sobered up fast.

Hokkeika (NYC)
January 15, 2018

This product is given at medical facilities in EU as a treatments course of infections, such as of the liver.

It’s also very efficient to treat upset stomach, diarrhea and hangover. Fear no more eating exotic food.

Kentzo
January 25, 2017

Amazing product

Amazing product that you have to have in your medicinal box! If you have poisoning or upset stomach it is the best thing to use! Helps quickly(well at least to me) it is safe to give to baby. I always have at least one in myhouse. I heard it can be used for bags under your eyes (planning to try it) and it is natural!

Alyon4ik
February 12, 2018

Calms a turbulent digestive track

Instantly calms a turbulent digestive track. Worth googling the presentation given on this product at Columbia University.

Gracie
July 26, 2017

This is an amazing corrective for digestive problems and hang overs

I take a tablespoon of this product and dissolve it in 4 oz of filtered water. Then down the hatch it goes. This is an amazing corrective for digestive problems and hang overs. I should be in everyone’s medicine cabinet! Why they don’t manufacture this product in the U.S. I don’t know. But it’s worth the price because it really does work 100%.

Michael R.
January 31, 2017

This works so great

This works so great for clearing up an intestinal irritation. It’s very soothing after you drink it.

Likesgoodthings
July 25, 2017

This product has helped to clear up some digestive problems I have been having

This product has helped to clear up some digestive problems I have been having. i am being conservative in giving it four stars because I have also been taking homeopathic advice and remedies and so cannot give all the credit to this product.

Olivia Sinton
August 6, 2016

Superb product

Seems to help detox after too much wine.
Superb product, but prices is inflated.

Bozone
May 26, 2017

Good product

Good product and does what it says.

Chris Moreton
October 27, 2017

Great product!

Wonderful special product but very expensive with the shipping, especially if you buy more and usually you need more than one – this is why I can just rate with 4 stars.

Claudia T.
December 14, 2015

Enterosgel helps

On second tube, even helps granddaughter when she is glutenated

P. Johnson (Alabama)
November 25, 2015

Works really fast

My subjective feelings are that 1 teaspoon has more efficiency than 10 capsules of activated charcoal (adsorbent agents) with 280 mg/each adsorbent power. It requires about 10-15 minutes to feel the effect and much less amount of water compared to activated charcoal. However, you still have to be careful when you try any new medication, and I would suggest to take a half of recommended dosage for the first time and wait for an hour, before taking the second half. Also, please note that the taste is terrible at first, but you will not notice it anymore after a few tries.

Irina Z.
February 26, 2017
Professional Opinion

The therapeutic effectiveness of Enterosgel has been demonstrated in: gastroenterology, infectious diseases, allergology, neurology, toxicology, gynaecology, and other nosologies.

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Where to Buy
ENTEROSGEL® is available in pharmacies and health stores all over the world.
RETAILERS WORLDWIDE