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2016, MODERN ENTEROSORPTION FOR PREVENTING EXACERBATIONS OF CHRONIC PATHOLOGY OF THE UPPER RESPIRATORY TRACT IN CHILDREN LIVING IN REGIONS WITH ECOLOGICAL TROUBLE

T.A. Esaulova, Yu.N. Sharikov, V.Ya. Dzhugostran

The results of the study evidenced high efficiency the course of healing with using the stimulation of lymphatic drainage and modern enterosorption (Enterosgel). This scheme can be recommended for widely used in prevention in children of school age with risk factors for prophylaxis and prevention of respiratory tract diseases progression.

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2016, ENTEROSORBENT ENTEROSGEL IN CLINICAL PRACTICE

T. Miksa

ln order to assess the characteristics of the medical device ENTEROSGEL, establish the method of its use and the safety for users, this report was drawn up in the form of a critical evaluation of the relevant published clinical studies conducted with ENTEROSGEL and with other at least partially comparable medical devices already placed on the European market.

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2015, ENTEROSORPTION IN EMERGENCE LUNG TUBERCULOSIS

Jugostran V.Ya., Sharikov Yu.N., Esaulova Т.А.

In a controlled open single center trials the results of chemotherapy newly diagnosed patients with pulmonary tuberculosis in combination with enterosorption one of three drugs: Enterosgel (polymethylsiloxane polyhydrate), aerosil or carbon sorbent. The effect on the performance of enterosorption intoxication and liver function during chemotherapy. As a result, due to hepatoprotective and detoxification effect enterosorption, managed to avoid the interruption of chemotherapy.

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2015, ENTEROSORPTION IN EMERGENCE LUNG TUBERCULOSIS

Jugostran V.Ya., Sharikov Yu.N., Esaulova Т.А.

In a controlled open single center trials the results of chemotherapy newly diagnosed patients with pulmonary tuberculosis in combination with enterosorption one of three drugs: Enterosgel (polymethylsiloxane polyhydrate), aerosil or carbon sorbent. The effect on the performance of enterosorption intoxication and liver function during chemotherapy. As a result, due to hepatoprotective and detoxification effect enterosorption, managed to avoid the interruption of chemotherapy.

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2015, COLLECTION OF RESEARCH PAPERS. ENTEROSGEL RESEARCHES

The term “enterosorption” has been proposed to define a method of sorption therapy based on daily oral administration of “enterosorbents”. Enterosorbents were known in the past because the tradition of eating natural clays in case of poisoning, for improvement of well-being, jugulation of diarrhea, and, possibly, for treatment of deficiency in microelements, goes back to bygone times, and as a phenomenon known as geophagia it was observed particularly in primates [6, 7]. However, Enterosgel, comparing to other sorbents has unique hydrophobic and selective sorption properties, which made it effective and safe in wide range of medical applications. Enterosgel has proven it’s safety and efficacy during 35 years of clinical studies and use in major hospitals of the Soviet Union, it is recommended in the official guidance of Ministry of Health for treatment of various diseases. Since 2008 Enterosgel is certified as a medical device class IIa and available as an OTC treatment in Europe.

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2014, SAFETY DATA SHEET

Bioline Products s.r.o.

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2014, COLLECTION OF RESEARCH PAPERS. GASTROENTEROLOGY: NEW APPROACHES

Extensive clinical experience on the use of an innovative intestinal adsorbent Enterosgel has been accumulated over the past 20 years. Enterosgel provides a wide range of the therapeutic effectiveness due to its ability to bind toxins, allergens and pathogens in the gastrointestinal tract and eliminate these from the body.

The results of clinical studies of using Enterosgel in gastroenterology are presented in the collection. Enterosgel has proven itself as an effective agent for the treatment of peptic ulcer disease, inflammatory bowel disease, and diseases of the liver.

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2013, UTILIZZO DEGLI ENTEROADSORBENTI IN BAMBINI ASMATICI CHE VIVONO IN CONDIZIONI SANITARIE PRECARIE

N. Zaitseva, O. Ustinova

ENTEROSORBENTS THERAPY IN CHILDREN WITH ASTHMA LIVING IN POOR SANITARY CONDITIONS

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2013, ENTEROSORBENTS THERAPY IN CHILDREN WITH ASTHMA LIVING IN POOR SANITARY CONDITIONS

Zaytseva N. , Usitnova O.

According to recent epidemiological and toxicological data, children living in poor sanitary conditions develop abnormal physical characteristics, such as morphological abnormalities and chronic diseases of the Central Nervous System and the respiratory, cardiovascular, musculoskeletal, endocrine and digestive Systems. Among the substances of industrial origin, an important role is played by metals that accumulate in the tissues and organs. The toxic effects are due to the type of metal, its concentration, the concurrence of other pathological factors and the general health conditions (immune reactivity, hypersensitivity, etc.). The study was conducted on 236 children suffering from mild asthma (experimental Group) living in areas close to metallurgical plants. 

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2013, COLLECTION OF RESEARCH PAPERS. ALLERGOLOGY, IMMUNOLOGY, DERMATOLOGY: NEW APPROACHES

Extensive clinical experience on the use of the innovative intestinal adsorbent Enterosgel has been accumulated over the past 20 years. Enterosgel provides a wide range of the therapeutic effectiveness due to its ability to bind toxins, harmful substances, pathogens and allergens in the gastrointestinal tract and eliminate these from the body. This collection of research papers presents study results of the application of Enterosgel in allergology, immunology and dermatology. Enterosgel was shown to be an effective treatment for asthma, dermal-respiratory syndrome, food allergy, urticaria, atopic dermatitis, acne vulgaris.

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2010, THE DETOXIFYING POTENTIAL AND CLINICAL EFFECTIVENESS OF THE ENTEROSORBENT ENTEROSGEL IN THE COMBINATION THERAPY OF VARIOUS DISEASES IN CHILDREN AND ADULTS

Nagornaya N.V., Dubovaya А.V.

The article describes different types of intoxication, presents a method of intracorporeal detoxification, and includes a classification of gastrointestinal adsorbents (enterosorbents). It summarizes the experience that has been gained with the intestinal adsorbent Enterosgel in the combination therapy of children and adults suffering from allergic diseases, gastrointestinal disorders, burn disease, chronic pyelonephritis, and recurrent non-specific vaginitis.

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2010, ENTEROSGEL

Nikolaev V.G.

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2010, ABOUT EXPERIMENTAL PRECLINICAL SAFETY STUDYING OF THE MEDICINAL FORM OF A PREPARATION «ENTEROSGEL®,PASTE FOR INTAKE (SWEET)» GIVEN «TNK SILMA LTD.» (MOSCOW)

THE STUDY DRUG SAFETY OF "ENTEROSGEL®, PASTA FOR INTAKE (SWEET)" ALLOWS TO RECOMMEND ITS SUBMISSION TO THE TO THE MINISTRY OF HEALTH OF THE RUSSIAN FEDERATION AS LOW-TOXICITY DRUG AS THE PROCEDURE FOR EXPANDING INDICATIONS AND CHANGES IN INSTRUCTION FOR USE.

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2009, APPLICATION OF THE METHOD OF ENTEROSORPTION THERAPY BY SILICON ENTEROSORBENT ENTEROSGEL IN THE INTEGRATED TREATMENT OF ALLERGIC DISEASES

J. Bystroň

Verification of clinical effectiveness and monitoring of the laboratoty values profile in patients with dermatic (atopic dermatitis, hibes) and respiratory (allergic asthma and allergic rhinitis) allergic symptoms in the period of main disease recrudescence. The influence of ENTEROSGEL taken was tested as a complementary influence in terms of the conventional basic treatment. For the purpose of making comparisons the same group of patients was monitored within the period prior to application of ENTEROSGEL. 

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2007, ENTEROSORPTION AS AN IMPORTANT METHOD OF TREATMENT OF ELIMINATING CHRONIC ENDOTOXIN AGGRESSION

Chernikhova E.A., Anikhovskaya I.A., Gataullin Yu.K., Zakirova D.Z., Ivanov V.B., Saveliev A.A., Yakovlev M.Yu.

The study of 25 patients with chronic inflammatory diseases (HID) in stage of remission has demonstrated efficiency of intestinal absorption method (enterosorption) to reduce significantly the total concentration of bacterial lipopolysaccharide (LPS) in the general circulation. Endotoxin aggression (EA) of intestinal etiology is a universal factor in the pathogenesis of many diseases and syndromes and may be the immediate cause of local inflammation, acute and chronic SIRS (systemic inflammatory response syndrome - systemic inflammatory response syndrome), allergic and autoimmune reactions.

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1998, EFFICACY OF THE CLINICAL APPLICATION OF ENTEROSGEL IN THE CLINICAL UNIT OF CHILDHOOS DISEASES OF I.M. SECHENOV MOSCOW MEDICAL ACADEMY

Baranov A.A., Geppe N.A., Karpushkina A.V.

The medication Enterosgel offered by the enterprise "SILMA" approved itself as the efficient agent for treatment of various allergic pathology. Taking of Enterosgel by patients having the atopic genesis of bronchial asthma and dermatitis helps to arrest the broncho-obstructive syndrome and skin syndrome due to adsorption of allergens. Enterosgel allowed patients to withdraw from antihistamine drugs, reduce the administration time of bronchial spasmolytics. It showed a high clinical activity in the therapy of both acute and chronic digestive diseases.
Thus, Enterosgel is the efficient supplement to conventional treatment of allergic and gastrointestinal diseases in children.

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1994, ON ESTABLISHMENT OF LARGE-SCALE PRODUCTION AND HEALTHCARE IMPLEMENTATION OF NOVEL HIGHLY EFFECTIVE POLYORGANOSILOXANE-BASED ADSORBENT DRUGS WITH DETOXIFYING EFFECT

Bezlyuda N.P., Baranyuk A.P.

Novel intestinal and topical adsorbent drugs with detoxifying effect (studies were conducted in 1980-1990 by order of Main Military Clinical Hospital of the Ministry of Defense of Ukraine) were widely evaluated in military medical facilities. The Military Hospital of Kyiv (nowadays the Main Military Clinical Hospital of the Ministry of Defense of Ukraine) participated in the medical and biological evaluation of novel drugs from the beginning of their development (V.N. Fadeev, F.G. Novikov, N.P. Bezlyuda). 

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